25 October 2026

DARPA's HUBBLE effort closes in 11 days, seeking an in-silico platform to map protein-protein interactions that could reveal new diagnostic and therapeutic targets for conditions such as traumatic brain injury. DARPA will host a Protein Palace Proposers Day on November 17, giving potential offerors a briefing before the solicitation is released. The agency also closes its Firefox program in 15 days, looking for approaches to build a non-invasive coherent optical brain-computer interface. Across the week three open requirements close within thirty days while none expire in the next seven. The Department of Defense leads the open pool with eight active solicitations, followed by one each from Energy and the National Science Foundation.