Biolab Mirror: Artificial Intelligence / Machine Learning (AI/ML) Digital Twin for Intent Characterization and Bio-Containment Integrity

Department of War · Defense Threat Reduction Agency · STTR Topic · 27.TZ

posted 4 November 2026 · closes 6 January 2027

Summary

The Department of War’s Defense Threat Reduction Agency seeks proposals to develop the Biolab Mirror, a high‑fidelity digital twin with AI/ML capabilities that continuously verifies integrity and characterizes intent at mid‑size BSL‑3/4 biological research facilities. The effort aims to create a physics‑based zero‑trust architecture that can detect clandestine pathogen production and provide a cyber‑physical sandbox for advanced security testing.

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